PRELIMINARY VALIDATION OF MRI-BASED MODELING FOR EVALUATION OF JOINT MECHANICS

Abstract

The objective of this study was to perform preliminary validation of MRI-based joint contact modeling methodology in the radiocarpal joints by comparison with the results of invasive radiocarpal contact measurements in three cadaver experiments. For each experiment, either Pressurex film or a Tekscan sensor was placed into the radiocarpal joints during a simulated grasp. Computer models were based on magnetic resonance imaging (MRI) of the cadaver specimens without load as well as on images acquired with the same loading used for the direct measurements. Geometric surface models of the radius, scaphoid, and lunate (including cartilage) were constructed from the images acquired without load. The carpal bone motions from the unloaded to the loaded state were determined using three-dimensional (3D) voxel image registration. Cartilage thickness was assumed to be uniform at 1.0 mm with an effective compressive modulus of 4 MPa. Resulting data included peak contact pressure, contact area, and contact force in the radioscaphoid and radiolunate joints. Contact area was also measured directly from MR images acquired with load and compared to model data. Qualitatively, there was good correspondence between the MRI-based model data and experimental data, with consistent relative size, shape, and location of radioscaphoid and radiolunate contact areas. Quantitative comparison of model and experimental data was reasonable, but less consistent. Contact area from the MRI-based model was always similar to the contact area measured directly from the MR images. With additional experiments, we believe that MRI-based joint contact modeling will soon be fully validated in the radiocarpal joints.