SECONDARY PULMONARY TUBERCULOSIS RECOGNITION BY ROTATION ANGLE VECTOR GRID-BASED FRACTIONAL FOURIER ENTROPY

Author:

WANG SHUI-HUA1,KARACA YELIZ2,ZHANG XIN3,ZHANG YU-DONG4

Affiliation:

1. School of Mathematics and Actuarial Science, University of Leicester, University Road, Leicester LE1 7RH, UK

2. University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA

3. Department of Medical Imaging, The Fourth People’s Hospital of Huai’an, Huai’an, Jiangsu 223002, P. R. China

4. School of Informatics, University of Leicester, University Road, Leicester LE1 7RH, UK

Abstract

Aim: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis bacteria. This study plans to build a novel deep learning-based model for the accurate recognition of tuberculosis. Methods: We propose a novel model — rotation angle vector grid-based fractional Fourier entropy and deep stacked sparse autoencoder (RAVG-FrFE–DSSAE) — which uses RAVG-FrFE as a feature extractor and harnesses DSSAE as the classifier. Moreover, an 18-way MDA is introduced on the training set to avoid overfitting. Results: Experimental results of 10 runs of 10-fold CV showcase that this proposed RAVG-FrFE–DSSAE algorithm yields a reasonable performance including of 93.68[Formula: see text]±[Formula: see text]1.11% sensitivity, 94.38[Formula: see text]±[Formula: see text]1.11% specificity, 94.35[Formula: see text]±[Formula: see text]1.04% precision, 94.03[Formula: see text]±[Formula: see text]0.69% accuracy, 94.01[Formula: see text]±[Formula: see text]0.70% [Formula: see text]-score, 88.07[Formula: see text]±[Formula: see text]1.38% MCC, 94.01[Formula: see text]±[Formula: see text]0.70% FMI, and 0.9725 AUC, respectively. Conclusions: Our result outperforms the eight state-of-the-art approaches. Besides, the result shows the effectiveness of the 18-way MDA.

Funder

Sino-UK Industrial Fund, UK

Global Challenges Research Fund (GCRF), UK

Royal Society International Exchanges Cost Share Award, UK

Medical Research Council Confidence in Concept Award, UK

Hope Foundation for Cancer Research, UK

British Heart Foundation Accelerator Award, UK

Publisher

World Scientific Pub Co Pte Ltd

Subject

Applied Mathematics,Geometry and Topology,Modelling and Simulation

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