Affiliation:
1. Khabarovsk Research Institute of Microbiology and Epidemiology
Abstract
Objective: to study the bacterial microflora in the sputum of patients with pneumonia caused by SARSCoV-2 or other pathogens.Materials and methods. The bacterial microflora of sputum of 173 patients with pneumonia admitted to hospitals in Khabarovsk and the Khabarovsk Territory in May – June 2020 was examined. Detection of RNA of the SARS-CoV-2 virus was carried out by PCR with the Vector-PCRRV-2019-nCoV-RG test system (manufactured by the State Scientific Center of VB “Vector”, Koltsovo). Determination of the DNA of mycoplasmosis agents and chlamydia was carried out with the test system “AmpliSens® Mycoplasma pneumoniae/Chlamydophila pneumonia” (manufactured by CRIE). Statistical data processing was performed using the Excel program. Results and discussion. Both groups of patients (Covid-19+ and Covid-19–) had high levels of bacterial flora isolation (81.4 and 74.7 %) including common pathogens for community-acquired pneumonia as well as notable detection frequency of Candida spp. and microbial associations. The group of Covid-19+ patients demonstrated a wider range of detected pathogens, was positive for poly-resistant gram-negative Enterobacteriaceae, non-fermenting gram-negative poly-resistant bacteria, with more expressed manifestation of microbial associations. In the group of Covid-19– participants drug-resistant microflora was presented only by MRSA and MRSE staphylococci.
Publisher
Russian Research Anti-Plague Institute Microbe
Subject
Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Epidemiology
Reference21 articles.
1. Chuchalin A.G., Sinopal’nikov A.I., Kozlov R.S., Tyurin I.E., Rachina S.A. [Community-acquired pneumonia in adults: practical recommendations on diagnostics, treatment and prevention (a manual for doctors)]. M.; 2010. 106 p.
2. Bayazitova L.T., Tyupkina O.F., Chazova T.A., Tyurin Yu.A., Isaeva G.S., Zaripova A.Z., Patyashina M.A., Avdonina L.G., Yuzlibaeva L.R. [Community-acquired pneumonia of pneumococcal etiology and microbiological aspects of nasopharyngeal carriage of Streptococcus pneumoniae in children in the Republic of Tatarstan]. Infektsiya i Immunitet [Russian Journal of Infection and Immunity]. 2017; 7(3):271–8. DOI: 10.15789/2220-7619-2017-3-271-278.
3. Brun-Busson Ch. Des germes si ordinaires. Le recherché. 1994; 25:706–9.
4. Goloverova Yu. A., Mar’in G.G., Shabalina S.V., Tutelyan A.V., Orlova O.A., Akimkin V.G. [Incidence of health care-associated infections in high-risk hospital units]. Infektsionnye Bolezni [Infectious Diseases]. 2019; 17(3):69–73. DOI: 10.20953/1729-9225-2019-3-69-73.
5. Orlova O.A., Akimkin V.G. [Organization of epidemiological diagnosis of ventilator-associated respiratory infections]. Meditsinskiy alfavit. Medical Alphabet 2017; 3(30): 15-19. (in Russian)
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