Author:
Rhodes Michael,Straw Richard,Fernando Supem,Evans Andrew,Lacey Tregaye,Dearlove Andrew,Greystrong John,Walker Joanne,Watson Paula,Weston Paul,Kelly Maria,Taylor Dilip,Gibson Keith,Mundy Chris,Bourgade Franck,Poirier Christophe,Simon Dominique,Brunialti Ana Lucia Bueno,Montagutelli Xavier,Gu′enet Jean-Louis,Haynes Andy,Brown Steve D.M.
Abstract
The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (Breen et al. 1994). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level (∼500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.
Publisher
Cold Spring Harbor Laboratory
Subject
Genetics(clinical),Genetics
Cited by
72 articles.
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