QRS detection in single-lead, telehealth electrocardiogram signals: benchmarking open-source algorithms

Author:

Kristof Florian,Kapsecker MaximilianORCID,Nissen LeonORCID,Brimicombe James,Cowie Martin R.ORCID,Ding ZixuanORCID,Dymond Andrew,Jonas Stephan M.ORCID,Clair Lindén Hannah,Lip Gregory Y. H.ORCID,Williams Kate,Mant JonathanORCID,Charlton Peter H.ORCID

Abstract

ABSTRACTBackground and ObjectivesA key step in electrocardiogram (ECG) analysis is the detection of QRS complexes, particularly for arrhythmia detection. Telehealth ECGs present a new challenge for automated analysis as they are noisier than traditional clinical ECGs. The aim of this study was to identify the best-performing open-source QRS detector for use with telehealth ECGs.MethodsThe performance of 18 open-source QRS detectors was assessed on six datasets. These included four datasets of ECGs collected under supervision, and two datasets of telehealth ECGs collected without clinical supervision. The telehealth ECGs, consisting of single-lead ECGs recorded between the hands, included a novel dataset of 479 ECGs collected in the SAFER study of screening for atrial fibrillation (AF). Performance was assessed against manual annotations.ResultsA total of 14 QRS detectors performed well on ECGs collected under clinical supervision (F1score ≥ 0.96). However, fewer performed well on telehealth ECGs: five performed well on the TELE ECG Database (F1of ≥ 0.99); six performed well on high-quality SAFER data (F1of ≥ 0.96); and performance was poorer on low-quality SAFER data (three QRS detectors achievedF1of 0.85-0.88). The presence of AF had little impact on performance.ConclusionsThe Neurokit, ‘two average’, and University of New South Wales QRS detectors performed best in this study. These performed sufficiently well on high-quality telehealth ECGs, but not on low-quality ECGs. This demonstrates the need to handle low-quality ECGs appropriately to ensure only ECGs which can be accurately analysed are used for clinical decision making.

Publisher

Cold Spring Harbor Laboratory

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