Abstract
AbstractDuring a fast-moving epidemic, timely monitoring of case counts and other key indicators of disease spread is critical to an effective public policy response. We describe a nonparametric statistical method, originally applied to the reporting of AIDS cases in the 1980s, to estimate the distribution of reporting delays of confirmed COVID-19 cases in New York City during the late summer and early fall of 2020. During August 15 - September 26, the estimated mean delay in reporting was 3.3 days, with 87 percent of cases reported by 5 days from diagnosis. Relying upon the estimated reporting-delay distribution, we projected COVID-19 incidence during the most recent three weeks as if each case had instead been reported on the same day that the underlying diagnostic test had been performed. Applying our delay-corrected estimates to case counts reported as of September 26, we projected a surge in new diagnoses that had already occurred but had yet to be reported. Our projections were consistent with counts of confirmed cases subsequently reported by November 7. The resulting estimate of recently diagnosed cases could have had an impact on timely policy decisions to tighten social distancing measures. While the recent advent of widespread rapid antigen testing has changed the diagnostic testing landscape considerably, delays in public reporting of SARS-CoV-2 case counts remain an important barrier to effective public health policy.
Publisher
Cold Spring Harbor Laboratory
Reference11 articles.
1. New York Department of Health and Mental Hygiene. case-hosp-death.csv (Comma-Separated-Value Data File). https://github.com/nychealth/coronavirus-data/blob/master/archive/case-hosp-death.csv: Last Commit, December 13, 2020 2020.
2. Harris JE . Failure of Concentric Regulatory Zones to Halt the Spread of COVID-19 in South Brooklyn, New York: October-November 2020. https://www.medrxiv.org/content/10.1101/2021.11.18.21266493v1: http://medRxiv.org, November 21 2021.
3. Maximum likelihood from incomplete data via the EM algorithm;Journal of the Royal Statistical Society, Ser B,1977
4. Lardieri A. De Blasio Warns of Reimposing Coronavirus Restrictions as New York Positivity Rate Rises. https://www.usnews.com/news/health-news/articles/2020-09-29/de-blasio-warns-of-reimposing-coronavirus-restrictions-as-new-york-positivity-rate-rises: US News, September 29 2020.
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献