Abstract
AbstractIn the mitochondrial genome, sexual asymmetry in transmission allows the accumulation of male-harming mutations since selection acts only on the effect of the mutation in females. Called the “Mother’s Curse”, this phenomenon induces a selective pressure for nuclear variants that compensate for this reduction in male fitness. Previous work has demonstrated the existence of these interactions and their potential to act as Dobzhansky–Muller incompatibilities, contributing to reproductive isolation between populations. However, it is not clear how readily they would give rise to and sustain hybrid incompatibilities. Here, we use computer simulations in SLiM 3 to investigate the consequences of sexually antagonistic mitochondrial-nuclear interactions in a subdivided population. We consider distinct migration schemes and vary the chromosomal location, and consequently the transmission pattern, of nuclear restorers. Disrupting these co-evolved interactions results in less-fit males, skewing the sex ratio toward females. Restoration of male fitness depends on both the chromosomal location of nuclear restorer loci and the migration scheme. Our results show that these interactions may act as Dobzhansky–Muller incompatibilities, but their strength is not enough to drive population isolation. Overall, this model shows the varied ways in which populations can respond to migration’s disruption of co-evolved mitochondrial-nuclear interactions.
Publisher
Cold Spring Harbor Laboratory
Reference86 articles.
1. Mayr E. Species, classification, and evolution. In: Biodiversity and Evolution. Tokyo: National Science Museum Foundation; 1995. p. 3–12.
2. Coyne J , Orr HA . Speciation. Sunderland, MA: Sinauer Associaties; 2004.
3. A Critique of the Species Concept in Biology
4. Mayr E. Systematics and the Origin of Species. New York: Columbia University Press; 1942.
5. Genetic Nature of Species Differences
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献