Early Detection Of COVID-19 Using A Smartwatch

Author:

Mishra TejaswiniORCID,Wang Meng,Metwally Ahmed A.ORCID,Bogu Gireesh K,Brooks Andrew WORCID,Bahmani Amir,Alavi Arash,Celli Alessandra,Higgs Emily,Dagan-Rosenfeld Orit,Fay Bethany,Kirkpatrick Susan,Kellogg RyanORCID,Gibson Michelle,Wang Tao,Rolnik Benjamin,Ganz Ariel B,Li Xiao,Snyder Michael PORCID

Abstract

AbstractWearable devices digitally measuring vital signs have been used for monitoring health and illness onset and have high potential for real-time monitoring and disease detection. As such they are potentially useful during public health crises, such as the current COVID-19 global pandemic. Using smartwatch data from 31 infected individuals identified from a cohort of over 5000 participants, we investigated the use of wearables for early, presymptomatic detection of COVID-19. From physiological and activity data, we first demonstrate that COVID-19 infections are associated with alterations in heart rate, steps and sleep in 80% of COVID-19 infection cases. Failure to detect these changes in the remaining patients often occurred in those with chronic respiratory/lung disease. Importantly the physiological alterations were detected prior to, or at, symptom onset in over 85% of the positive cases (21/24), in some cases nine or more days before symptoms. Through daily surveys we can track physiological changes with symptom onset and severity. Finally, we develop a method to detect onset of COVID-19 infection in real-time which detects 67% of infection cases at or before symptom onset. Our study provides a roadmap to a rapid and universal diagnostic method for the large-scale detection of respiratory viral infections in advance of symptoms, highlighting a useful approach for managing epidemics using digital tracking and health monitoring.

Publisher

Cold Spring Harbor Laboratory

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