Author:
Dunn Gavin P.,Rinne Mikael L.,Wykosky Jill,Genovese Giannicola,Quayle Steven N.,Dunn Ian F.,Agarwalla Pankaj K.,Chheda Milan G.,Campos Benito,Wang Alan,Brennan Cameron,Ligon Keith L.,Furnari Frank,Cavenee Webster K.,Depinho Ronald A.,Chin Lynda,Hahn William C.
Abstract
Glioblastoma is both the most common and lethal primary malignant brain tumor. Extensive multiplatform genomic characterization has provided a higher-resolution picture of the molecular alterations underlying this disease. These studies provide the emerging view that “glioblastoma” represents several histologically similar yet molecularly heterogeneous diseases, which influences taxonomic classification systems, prognosis, and therapeutic decisions.
Publisher
Cold Spring Harbor Laboratory
Subject
Developmental Biology,Genetics
Cited by
441 articles.
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