Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma-Reference-Cited by-同舟云学术

Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma

Published:2024-01-16 Issue:2 Volume:15 Page:258-264
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kim Dalton R.¹²,Orr Meghan J.¹²,Yu Xiaozhou³⁴,Munshi Hasan H.¹,Wang Austin²,Trudeau Claire¹,Kwong Ada J.¹^ORCID,Cheng Shi-Yuan³⁴^ORCID,Scheidt Karl A.¹⁵⁶^ORCID

Affiliation:

1. Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States

2. Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States

3. Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States

4. The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois 60611, United States

5. Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208, United States

6. Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, United States

Funder

National Cancer Institute

National Institute of Neurological Disorders and Stroke

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00505

Reference35 articles.

1. Overcoming therapeutic resistance in glioblastoma: the way forward

2. Malignant Gliomas in Adults

3. Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

4. Glioblastoma: Overview of Disease and Treatment

5. Emerging insights into the molecular and cellular basis of glioblastoma

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