Abstract
AbstractWe develop a minimal compartmental model to analyze policies on mobility restriction in Italy during the Covid-19 outbreak. Our findings show that a premature lockdown barely shifts the epidemic in time: moreover, beyond a critical value of the lockdown strength, an epidemic that seems to be quelled fully recovers after lifting the restrictions. We investigate the effects on lockdown scenarios and exit strategies by introducing heterogeneities in the model. In particular, we consider Italian regions as separate administrative entities in which social interactions through different age classes occur. We find that, due to the sparsity of the mobility matrix, epidemics develop independently in different regions once the outbreak starts. Moreover, after the epidemics ha started, the influence of contacts with other regions becomes soon irrelevant. Sparsity might be responsible for the observed delays among different regions. Analogous arguments apply to the world/countries scenario. We also find that disregarding the structure of social contacts could lead to severe underestimation of the post-lockdown effects. Nevertheless, age class based strategies can help to mitigate rebound effects with milder strategies. Finally, we point out that these results can be generalized beyond this particular model by providing a description of the effects of key parameters on non-medical epidemic mitigation strategies.
Publisher
Cold Spring Harbor Laboratory
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献