Abstract
AbstractHere we report that a chemical cocktail (LCDM: hLIF,CHIR99021,DiM andMiH) previously used for extended potential pluripotent stem cells enables the de novo derivation and long-term culture of bovine trophoblast stem cells (TSCs). Bovine TSCs exhibit transcriptomic and epigenetic features characteristic of trophectoderm cells from bovine embryos and retain developmental potency to differentiate into mature trophoblast cells.
Publisher
Cold Spring Harbor Laboratory
Cited by
1 articles.
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