Interim estimates of increased transmissibility, growth rate, and reproduction number of the Covid-19 B.1.617.2 variant of concern in the United Kingdom

Author:

Dagpunar JohnORCID

Abstract

AbstractThis paper relates to data from the Wellcome Sanger Institute, UK, regarding Covid-19 genomic surveillance. We use a simple model to give point estimates of the effective reproduction numbers of the B.1.617.2 and B.1.1.7 lineages in England, from sequenced data as at 15 May 2021. Comparison with the estimated reproduction number of B.1.1.7 enables an estimate of the increased transmissibility of B.1.617.2. We conclude that it is almost certain that there is increased transmissibility that will rapidly lead to B.1.617.2 becoming the prevailing variant in the UK. The derived estimates of increased transmissibility have uncertainty relating to the actual distribution of the generation interval, but they do point, under present conditions of vaccination coverage and NPIs, to exponential growth of positive cases.

Publisher

Cold Spring Harbor Laboratory

Reference9 articles.

1. Wellcome Sanger Institute, Covid 19 Genomic Survey. https://covid19.sanger.ac.uk/lineages/raw?show=B.1.617.2%2CB.1.1.7&colorBy=p&lineage=B.1.617.2&area=overview&latitude=50.161569&longitude=-2.591175&zoom=4.33&date=2021-05-22

2. Coronavirus (Covid-19) in the UK, Cases in England. https://coronavirus.data.gov.uk/details/cases?areaType=nation&areaName=England

3. Public Heath England (2021). SARS-CoV-2 variants of concern and variants under investigation in England, Technical briefing 13, 27 May 2021. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/990339/Variants_of_Concern_VOC_Technical_Briefing_13_England.pdf

4. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

5. How generation intervals shape the relationship between growth rates and reproductive numbers

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