Combination Informatic and Experimental Approach for Selecting Scaffold Proteins for Development as Antibody Mimetics-Reference-Cited by-同舟云学术

Combination Informatic and Experimental Approach for Selecting Scaffold Proteins for Development as Antibody Mimetics

Published:2021-11-05 Issue:11 Volume:50 Page:1867-1871
ISSN:0366-7022
Container-title:Chemistry Letters
language:en
Short-container-title:Chem. Lett.

Author:

Ito Tomoyuki¹,Nishi Hafumi²³⁴,Kameda Tomoshi⁵⁶,Yoshida Mayu¹,Fukazawa Reito¹,Kawada Sakiya¹,Nakazawa Hikaru¹,Umetsu Mitsuo¹⁶

Affiliation:

1. Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, 6-6-11 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579, Japan

2. Department of Applied Information Sciences, Graduate School of Information Science, Tohoku University, 6-3-09 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579, Japan

3. Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan

4. Faculty of Core Research, Ochanomizu University, 2-1-1 Ohtsuka, Bunkyo-ku, Tokyo 112-8610, Japan

5. Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan

6. Center for Advanced Intelligence Project, RIKEN, 1-4-1 Nihombashi, Chuo-ku, Tokyo 103-0027, Japan

Publisher

The Chemical Society of Japan

Subject

General Chemistry

Link

http://www.journal.csj.jp/doi/pdf/10.1246/cl.210443

Reference27 articles.

1. Antibody Structure and Function: The Basis for Engineering Therapeutics

2. Engineered protein scaffolds as next-generation antibody therapeutics

3. The Effect of Molecular Weight, PK, and Valency on Tumor Biodistribution and Efficacy of Antibody-Based Drugs

4. Engineering of binding functions into proteins

5. Challenges and opportunities for non-antibody scaffold drugs

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In silico designing and optimization of anti‐epidermal growth factor receptor scaffolds by complementary‐determining regions‐grafting technique;Quantitative Biology;2024-07-10

2. Extensive antibody search with whole spectrum black-box optimization;Scientific Reports;2024-01-04

3. Physicochemical, functional, and evolutionary characteristics of protein loop regions in human andEscherichia coliproteomes;2023-06-11

4. Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning;mAbs;2023-01-22