The Effect of Molecular Weight, PK, and Valency on Tumor Biodistribution and Efficacy of Antibody-Based Drugs

Author:

Muchekehu Ruth,Liu Dingguo,Horn Mark,Campbell Lioudmila,Del Rosario Joselyn,Bacica Michael,Moskowitz Haim,Osothprarop Trina,Dirksen Anouk,Doppalapudi Venkata,Kaspar Allan,Pirie-Shepherd Steven R.,Coronella Julia

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference38 articles.

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2. Antibodies as carriers of cytotoxicity. Contributions to Oncology;Sedlacek,1992

3. Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids;Ackerman;Mol Cancer Ther,2008

4. Intermittent blood flow in a murine tumor: radiobiological effects;Chaplin;Cancer Res,1987

5. High interstitial fluid pressure—an obstacle in cancer therapy;Heldin;Nat Rev Cancer,2004

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