Immunization Therapy for Alzheimer Disease: A Comprehensive Review of Active Immunization Strategies
Author:
Affiliation:
1. Department of Diagnosis, Prevention and Treatment of Dementia, Graduate School of Juntendo University
Publisher
Tohoku University Medical Press
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.jstage.jst.go.jp/article/tjem/220/2/220_2_95/_pdf
Reference65 articles.
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2. Bach, P., Tschäpe, J.A., Kopietz, F., Braun, G., Baade, J.K., Wiederhold, K.H., Staufenbiel, M., Prinz, M., Deller, T., Kalinke, U., Buchholz, C.J. & Müller, U.C. (2009) Vaccination with Aβ-displaying virus-like particles reduces soluble and insoluble cerebral Aβ and lowers plaque burden in APP transgenic mice. J. Immunol., 182, 7613-7624.
3. Bard, F., Cannon, C., Barbour, R., Burke, R.L., Games, D., Grajeda H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Lieberburg, I., Motter, R., Nguyen, M., Soriano, F., Vasquez, N., Weiss, K., Welch, B., Seubert, P., Schenk, D. & Yednock, T. (2000) Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med., 6, 916-919.
4. Epitope and isotype specificities of antibodies to -amyloid peptide for protection against Alzheimer's disease-like neuropathology
5. Boutajangout, A., Goni, F., Knudsen, E., Schreiber, F., Asuni, A., Quartermain, D., Frangione, B., Chabalgoity, A., Wisniewski, T. & Sigurdsson, E.M. (2009) Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a Salmonella-based amyloid-beta derivative vaccine. J. Alzheimers Dis., 18, 961-972.
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