Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease-Reference-Cited by-同舟云学术

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Published:2000-08 Issue:8 Volume:6 Page:916-919
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Bard Frédérique,Cannon Catherine,Barbour Robin,Burke Rae-Lyn,Games Dora,Grajeda Henry,Guido Teresa,Hu Kang,Huang Jiping,Johnson-Wood Kelly,Khan Karen,Kholodenko Dora,Lee Mike,Lieberburg Ivan,Motter Ruth,Nguyen Minh,Soriano Ferdie,Vasquez Nicki,Weiss Kim,Welch Brent,Seubert Peter,Schenk Dale,Yednock Ted

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm0800_916.pdf

Reference10 articles.

1. Games, D. et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373, 523–527 (1995).

2. Masliah, E. et al. Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16, 5795–57811 (1996).

3. Schenk, D. et al. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400, 173–177 (1999).

4. St. George-Hyslop, P.H. & Westaway, D.A. Alzheimer's disease: antibody clears senile plaques. Nature 400, 116–117 (1999).

5. Duff, K. Curing amyloidosis: will it work in humans? Trends Neurosci. 22, 485–486 (1999).

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