Blockade of the Wnt/.BETA.-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis
Author:
Affiliation:
1. Department of Internal Medicine, Hanyang University College of Medicine
2. Department of Bioengineering, Hanyang University
Publisher
Tohoku University Medical Press
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.jstage.jst.go.jp/article/tjem/223/1/223_1_45/_pdf
Reference49 articles.
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2. Simple method of estimating severity of pulmonary fibrosis on a numerical scale.
3. Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls
4. Brabletz, T., Jung, A., Dag, S., Hlubek, F. & Kirchner, T. (1999) Beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am. J. Pathol., 155, 1033-1038.
5. Cheng, J.H., She, H., Han, Y.P., Wang, J., Xiong, S., Asahina, K. & Tsukamoto, H. (2008) Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol., 294, G39-49.
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