A New Route to 2,3-Dihydro-1,5-Benzothiazepines from Nitrodisulfides and α,β-Unsaturated Ketones by Smi2-Reference-Cited by-同舟云学术

A New Route to 2,3-Dihydro-1,5-Benzothiazepines from Nitrodisulfides and α,β-Unsaturated Ketones by Smi2

Published:2000-08 Issue:8 Volume:2000 Page:386-387
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Chen Xiaoyuan¹,Zhong Weihui²,Zhang Yongmin²³

Affiliation:

1. Department of Chemistry, Hunan Jishou University, Jishou, 416000, P.R. China

2. Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou, 310028, PR China

3. Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, PR China

Abstract

Nitrodisulfides on treatment with SmI2 in anhydrous THF at room temperature lead to reactive intermediates, which are “living” double-anions and react smoothly with α,β-unsaturated ketones to afford 2,3-dihydro-1,5-benzothiazepines in good yields under mild and neutral conditions.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/030823400103167778

Reference21 articles.

1. Effects of Antihypertensive Drugs on Cholesterol Metabolism of Human Mononuclear Leukocytes and Hepatoma Cells

2. 5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice

3. Über heterocyclische Siebenringsysteme, VIII. Synthesen Kondensierter 7‐Gliedriger Heterocyclen mit 1 Stickstoff‐ und 1 Schwefelatom

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