A simple green protocol for the synthesis of ethyl 3-amino-1-aryl-1H-benzo[f] chromene-2-carboxylates in aqueous media-Reference-Cited by-同舟云学术

A simple green protocol for the synthesis of ethyl 3-amino-1-aryl-1H-benzo[f] chromene-2-carboxylates in aqueous media

Published:2017-08 Issue:8 Volume:41 Page:487-490
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Qian Siran¹,Li Mingjie¹,Liu Jiaming¹,Wang Cunde¹

Affiliation:

1. School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P.R. China.

Abstract

An eco-friendly and efficient straightforward method has been developed for the synthesis of ethyl 3-amino-1-aryl-1 H-benzo[ f]chromene-2-carboxylate derivatives via 1,4-diazabicyclo[2.2.2]octane (DABCO)-catalysed cyclisation of β-naphthol and 3-aryl-2-cyanoacrylates using water as a green solvent. All products precipitated from the reaction mixture and were isolated by simple filtration. No further work-up nor purification was necessary. The structure of ethyl 3-amino-1-aryl-1 H-benzo[ f]chromene-2-carboxylate was further confirmed by X-ray single crystal analysis.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751917X15016663252830

Reference32 articles.

1. Potentiation of the antiviral activity of poly r(A-U) by xanthene dyes

2. Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

3. Synthesis, antifungal activity and docking study of 2-amino-4H-benzochromene-3-carbonitrile derivatives

4. Synthesis of halogen derivatives of benzo[h]chromene and benzo[a]anthracene with promising antimicrobial activities

5. Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s Disease

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The versatility of DABCO: synthetic applications of its basic, nucleophilic, and catalytic properties Part 2*. Catalysis of Michael and Biginelli reactions and nucleophilic addition at C=X and C≡X bonds;Chemistry of Heterocyclic Compounds;2020-02