Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides-Reference-Cited by-同舟云学术

Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Published:1998-02-18 Issue:6 Volume:41 Page:787-797
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Smith Paul W.¹,Sollis Steven L.¹,Howes Peter D.¹,Cherry Peter C.¹,Starkey Ian D.¹,Cobley Kevin N.¹,Weston Helen¹,Scicinski Jan¹,Merritt Andrew¹,Whittington Andrew¹,Wyatt Paul¹,Taylor Neil¹,Green Darren¹,Bethell Richard¹,Madar Safia¹,Fenton Robert J.¹,Morley Peter J.¹,Pateman Tony¹,Beresford Alan¹

Affiliation:

1. Departments of Enzyme Medicinal Chemistry, Core Combinatorial Group, Biomolecular Structure, Enzyme Pharmacology, Systems Biology, and Drug Metabolism, Glaxo Wellcome Research and Development Limited, Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts SG1 2NY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970374b

Reference37 articles.

1. Impact of influenza and respiratory syncytial virus on mortality in England and Wales from January 1975 to December 1990

2. SERIOUS MORBIDITY AND MORTALITY ASSOCIATED WITH INFLUENZA EPIDEMICS

3. Design and antiviral properties of influenza virus neuraminidase inhibitors

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