A Practical and Diastereoselective Synthesis of Dihydrofurocoumarin from Pyridinium Ylides in Aqueous Medium-Reference-Cited by-同舟云学术

A Practical and Diastereoselective Synthesis of Dihydrofurocoumarin from Pyridinium Ylides in Aqueous Medium

Published:2016-11 Issue:11 Volume:40 Page:698-703
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

An Litao¹,Sun Xiaojun¹,Zhang Lulu¹,Zhou Jianfeng¹,Zhu Fengxia¹,Shen Zhengjia¹

Affiliation:

1. Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials, College of Chemistry and Chemical Engineering, Huaiyin Normal University, Huaian 223300, Jiangsu Province, P.R. China

Abstract

A series of 2,3-dihydrofurocoumarins were prepared via a three-component reaction of aldehyde, pyridinium salt and 4-hydroxycoumarin in aqueous ethanol. This method avoids using excessive pyridine and trimethylamine, and has operational simplicity and avoids tedious column chromatography purification. Both aryl aldehydes and aliphatic aldehydes are applicable to this protocol.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751916X14768944130291

Reference26 articles.

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