Recent Advances on Sustainable Synthesis of Furocoumarins

Abstract

AbstractBeing an important constituent of naturally occurring heterocyclic compounds with a myriad of interesting biological activities, the furocoumarin motif has claimed vast interest in synthetic and medicinal research. Designing organic synthesis following a green and sustainable approach finds special importance in terms of energy efficiency, and cost‐effectiveness and hence becoming an important domain of research in the recent past. The methodologies for the sustainable synthesis of furocoumarin presented here particularly include the strategies developed under microwave irradiation, solvent‐free conditions or uses of green solvent, metal‐free routes, room temperature mediated and following one‐pot MCR reactions. This review article attempts to highlight the recent advances in the sustainable synthesis of furocoumarins along with general aspects like natural occurrence, and biological activities of this particular heterocyclic scaffold.