Use of Disubstituted Thiosemicarbazide in Synthesis of New Derivatives of 1,3,4-Thiadiazole, 1,2,4-Triazole and Pyrazole with Their Antimicrobial Evaluation-Reference-Cited by-同舟云学术

Use of Disubstituted Thiosemicarbazide in Synthesis of New Derivatives of 1,3,4-Thiadiazole, 1,2,4-Triazole and Pyrazole with Their Antimicrobial Evaluation

Published:2016-06 Issue:6 Volume:40 Page:345-350
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Hemdan Magdy M.¹,El-Mawgoude Heba K. Abd²

Affiliation:

1. Department of Chemistry, Faculty of Science, Ain Shams University, 11566 Abbasia, Cairo, Egypt

2. Department of Chemistry, Faculty of Women, Ain Shams University, 11767 Heliopolis, Cairo, Egypt

Abstract

New derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and pyrazole were obtained by cyclisation of the corresponding disubstituted thiosemicarbazide derivative. The newly synthesised derivatives were obtained in good yields and their structures were elucidated by spectral data and elemental analyses. The antimicrobial activity of some of the synthesised compounds is tested.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751916X14622845946035

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2. New 1,3,4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities

3. Synthesis and antiproliferative activity of some 5-substituted 2-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles

4. Synthesis of 2-Amino-5-sulfanyl-1,3,4-thiadiazole Derivatives and Evaluation of Their Antidepressant and Anxiolytic Activity

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