Synthesis of new derivatives of 4-(4-methyl-5H-pyrimido[4,5-b][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5H-pyrimido[4,5-b][1,4]thiazine-Reference-Cited by-同舟云学术

Synthesis of new derivatives of 4-(4-methyl-5H-pyrimido[4,5-b][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5H-pyrimido[4,5-b][1,4]thiazine

Published:2017-07 Issue:7 Volume:41 Page:406-407
ISSN:1747-5198
Container-title:Journal of Chemical Research
language:en
Short-container-title:Journal of Chemical Research

Author:

Karimian Azam¹,Karimian Hassan²

Affiliation:

1. Department of Chemistry, Faculty of Sciences, University of Gonabad, Gonabad, Iran

2. Department of Environment, Faculty of Environment, University of Tehran, Tehran, Iran

Abstract

Several derivatives of the novel 4-(4-methyl-5 H-pyrimido[4,5- b][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5 H-pyrimido[4,5- b][1,4]thiazine ring systems have been synthesised through cyclocondensation of 5-amino-6-methylpyrimidine-4-thiols and the appropriate α-haloketone in glacial acetic acid under reflux.

Publisher

SAGE Publications

Subject

General Chemistry

Link

http://journals.sagepub.com/doi/pdf/10.3184/174751917X14967701767049

Reference29 articles.

1. Synthesis of pyrimidine-2,4,6-trione derivatives: Anti-oxidant, anti-cancer, α-glucosidase, β-glucuronidase inhibition and their molecular docking studies

2. Discovery of (2S)-8-[(3R)-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

3. Synthesis of bis(trifluoromethyl)pyrimido[4,5-d]pyrimidine-2,4-diones and evaluation of their antibacterial and antifungal activities

4. Synthesis of new 2-substituted pyrido[2,3-d]pyrimidin-4(1H)-ones and their antibacterial activity☆

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