1. MRC CAiTE Centre, Department of Social Medicine (NJT and GDS) and the Department of Community Based Medicine (PME), Bristol University, Bristol, United Kingdom; Genetics of Complex Traits (TMF and ATH) and Diabetes Genetics (TMF and ATH), Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, United Kingdom; the School of Pharmacy and Biomolecular Sciences, University of