Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Workers in South Africa: A Longitudinal Cohort Study-Reference-Cited by-同舟云学术

Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Workers in South Africa: A Longitudinal Cohort Study

Published:2021-05-05 Issue:10 Volume:73 Page:1896-1900
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Nunes Marta C¹²^ORCID,Baillie Vicky L¹²,Kwatra Gaurav¹²,Bhikha Sutika¹²,Verwey Charl¹³,Menezes Colin⁴,Cutland Clare L¹²⁵,Moore David P¹³,Dangor Ziyaad¹³,Adam Yasmin⁶,Mathivha Rudo⁷,Velaphi Sithembiso C³,Tsitsi Merika⁴,Aguas Ricardo⁸,Madhi Shabir A¹²⁵,Nakwa Firdose,Van Blydenstein Sarah,Venter Michelle,Reddy Denasha,du Plessis Jeanine,Laubscher Matt,van der Merwe Lara,Mbele Nkululeko,Mukendi Beya,McKenzie Shakeel,Mtshali Sihle,Mukendi Christian Kabasele,Nzimande Ayanda,Mandindi Wendy Zimkhitha,Nana Amit Jawaharlal,Rafuma Martin Mosotho,Mathibe Masego Nicole,Moultrie Andrew,

Affiliation:

1. South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

2. Department of Science and Technology/National Research Foundation, South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

3. Department of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

4. Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

5. African Leadership in Vaccinology Expertise, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

6. Department of Obstetrics & Gynaecology, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

7. Department of Intensive Care, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

8. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Abstract

Abstract From April to September 2020, we investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a cohort of 396 healthcare workers (HCWs) from 5 departments at Chris Hani Baragwanath Hospital, South Africa. Overall, 34.6% of HCWs had polymerase chain reaction–confirmed SARS-CoV-2 infection (132.1 [95% confidence interval, 111.8–156.2] infections per 1000 person-months); an additional 27 infections were identified by serology. HCWs in the internal medicine department had the highest rate of infection (61.7%). Among polymerase chain reaction–confirmed cases, 10.4% remained asymptomatic, 30.4% were presymptomatic, and 59.3% were symptomatic.

Funder

European and Developing Countries Clinical Trials Partnership

Bill and Melinda Gates Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciab398/38594993/ciab398.pdf

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