1. Department of Biostatistics, University of Iowa, Iowa City, IA 52242, USA
2. Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
3. Key laboratory of Genetics Network Biology, Collaborative Innovation Center of Genetics and Development, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
4. University of Chinese Academy of Sciences, Beijing 100049, China