Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks

Author:

Kuhar Ryan1,Gwiazda Kamila S.11,Humbert Olivier1,Mandt Tyler1,Pangallo Joey1,Brault Michelle1,Khan Iram1,Maizels Nancy11,Rawlings David J.11,Scharenberg Andrew M.11,Certo Michael T.1

Affiliation:

1. Center of Immunity and Immunotherapies, Seattle Children’s Research Institute, Seattle, 98101 Washington, USA, 2Program in Molecular and Cellular Biology, University of Washington, Seattle, 98195 Washington, USA, 3Department of Immunology, University of Washington, Seattle, 98195 Washington, USA and 4Department of Biochemistry, University of Washington, Seattle, 98195 Washington, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference47 articles.

1. Development of nuclease-mediated site-specific genome modification;Wirt;Curr. Opin. Immunol.,2012

2. Targeted gene therapies: tools, applications, optimization;Humbert;Crit. Rev. Biochem. Mol. Biol.,2012

3. Genetic steps of mammalian homologous repair with distinct mutagenic consequences;Stark;Mol. Cell. Biol.,2004

4. Genome editing with engineered zinc finger nucleases;Urnov;Nat. Rev. Genet.,2010

5. Targeted genome editing in pluripotent stem cells using zinc-finger nucleases;Bobis-Wozowicz;Methods,2011

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