A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors

Author:

Chen Zexiang1,Kwan Suet-Yan1,Mir Aamir1ORCID,Hazeltine Max1,Shin Minwook1,Liang Shun-Qing1ORCID,Chan Io Long1,Kelly Karen1,Ghanta Krishna S.1,Gaston Nicholas1ORCID,Cao Yueying1,Xie Jun23456,Gao Guangping23456,Xue Wen1278,Sontheimer Erik J.1279ORCID,Watts Jonathan K.1239ORCID

Affiliation:

1. RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

2. Li Weibo Institute for Rare Diseases Research, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

3. NeuroNexus Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

4. Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

5. Viral Vector Core, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

6. Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

7. Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

8. Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

9. Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Biotechnology

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