CRISPR technology: A decade of genome editing is only the beginning-Reference-Cited by-同舟云学术

CRISPR technology: A decade of genome editing is only the beginning

Published:2023-01-20 Issue:6629 Volume:379 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Wang Joy Y.¹²^ORCID,Doudna Jennifer A.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.

2. Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.

3. Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.

4. Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

5. California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.

Abstract

The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome editing, coupled with advances in computing and imaging capabilities, has initiated a new era in which genetic diseases and individual disease susceptibilities are both predictable and actionable. Likewise, genes responsible for plant traits can be identified and altered quickly, transforming the pace of agricultural research and plant breeding. In this Review, we discuss the current state of CRISPR-mediated genetic manipulation in human cells, animals, and plants along with relevant successes and challenges and present a roadmap for the future of this technology.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Link

https://www.science.org/doi/pdf/10.1126/science.add8643

Reference200 articles.

1. Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

2. Intervening Sequences of Regularly Spaced Prokaryotic Repeats Derive from Foreign Genetic Elements

3. Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

4. CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

5. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

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