1. From the Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom (RR, ASB, BAF, MF-FC, MG, FK, and KNF); the Department of Human Biology, Maastricht University and University Hospital, Maastricht, Netherlands (EEB); and the School of Sport and Exercise Sciences, University of Birmingham, Birmingham, United Kingdom (AJW)