Trajectories of Preexposure Prophylaxis Adherence Among Commercially Insured Individuals

Author:

Unigwe Ikenna1,Goodin Amie1,Lo-Ciganic Wei-Hsuan234ORCID,Cook Robert L5,Park Haesuk1ORCID

Affiliation:

1. Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida , Gainesville, Florida , USA

2. Division of General Internal Medicine, School of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania , USA

3. Center for Pharmaceutical Policy and Prescribing, Health Policy Institute, University of Pittsburgh , Pittsburgh, Pennsylvania , USA

4. North Florida/South Georgia Veterans Health System, Geriatric Research Education and Clinical Center , Gainesville, Florida , USA

5. Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida , Gainesville, Florida , USA

Abstract

Abstract We used group-based trajectory models to identify 4 distinct trajectory patterns of adherence to preexposure prophylaxis (PrEP) among 20 696 users. Only 44.5% were consistently PrEP adherent, with younger age, being female, or having substance use disorder or depression associated with early discontinuation. Public health efforts are needed to improve PrEP adherence.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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