Structure-activity relationship in advanced glycation end products formation inhibitory activity of phlorotannins-Reference-Cited by-同舟云学术

Structure-activity relationship in advanced glycation end products formation inhibitory activity of phlorotannins

Published:2022-07-01 Issue:9 Volume:86 Page:1207-1210
ISSN:1347-6947
Container-title:Bioscience, Biotechnology, and Biochemistry
language:en
Short-container-title:

Author:

Sekiguchi Mitsuhiro¹^ORCID,Shinoda Seiya¹,Uno Arisa¹,Masaki Tomoya¹,Sasaki Tetsuya²^ORCID,Ishiyama Haruaki³

Affiliation:

1. Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University , Nonoichi, Ishikawa, Japan

2. Chemistry/Food Department, Industrial Research Institute of Ishikawa , Kanazawa, Ishikawa, Japan

3. School of Pharmaceutical Sciences, Ohu University , Koriyama, Fukushima, Japan

Abstract

ABSTRACT The structure and inhibitory activity of advanced glycation end products (AGEs) formation were studied using six model compounds and seven phlorotannins isolated from brown alga Ecklonia stolonifera. As a result, it was inferred that AGEs formation inhibitory activity was stronger when electron-rich groups were present because of the addition of many oxygen atoms to the phlorotannins.

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Link

https://academic.oup.com/bbb/advance-article-pdf/doi/10.1093/bbb/zbac106/45322153/zbac106.pdf

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