Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site-Reference-Cited by-同舟云学术

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Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site

Published:2018-06-14 Issue:14 Volume:46 Page:7296-7308
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Cao Nan¹²,Tan Kemin³,Annamalai Thirunavukkarasu¹²,Joachimiak Andrzej³,Tse-Dinh Yuk-Ching¹²

Affiliation:

1. Department of Chemistry and Biochemistry, Florida International University, 11200 SW 8 St, Miami, FL 33199, USA

2. Biomolecular Sciences Institute, Florida International University, 11200 SW 8 St, Miami, FL 33199, USA

3. Structural Biology Center, Biosciences, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA

Funder

National Institute of Health

U.S. Department of Energy, Office of Biological and Environmental Research

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/14/7296/25509813/gky492.pdf

Reference57 articles.

1. DNA topoisomerase I and DNA gyrase as targets for TB therapy;Nagaraja;Drug Discov. Today,2017

2. Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target;Ravishankar;Tuberculosis (Edinb),2015

3. Conditional silencing of topoisomerase I gene of Mycobacterium tuberculosis validates its essentiality for cell survival;Ahmed;FEMS Microbiol. Lett.,2014

4. New mechanistic and functional insights into DNA topoisomerases;Chen;Annu. Rev. Biochem.,2013

5. All tangled up: how cells direct, manage and exploit topoisomerase function;Vos;Nat. Rev. Mol. Cell Biol.,2011

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2. Variation of Structure and Cellular Functions of Type IA Topoisomerases across the Tree of Life;Cells;2024-03-21

3. Alkaloids and Quinolones as potential MtbTopI inhibitors: An in-silico discovery using ADME studies and molecular dynamics simulation;2023-10-30

4. What’s on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases;International Journal of Molecular Sciences;2023-02-16

5. The interaction between transport-segment DNA and topoisomerase IA—crystal structure of MtbTOP1 in complex with both G- and T-segments;Nucleic Acids Research;2022-12-30

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