Conditional silencing of topoisomerase I gene ofMycobacterium tuberculosisvalidates its essentiality for cell survival
Author:
Affiliation:
1. Department of Microbiology and Cell Biology; Indian Institute of Science; Bangalore India
2. Jawaharlal Nehru Centre for Advanced Scientific Research; Bangalore India
Publisher
Oxford University Press (OUP)
Subject
Genetics,Molecular Biology,Microbiology
Link
http://academic.oup.com/femsle/article-pdf/353/2/116/19120955/353-2-116.pdf
Reference33 articles.
1. Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol;Annamalai;BMC Biochem,2009
2. Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies;Azarova;P Natl Acad Sci USA,2007
3. Development of a repressible mycobacterial promoter system based on two transcriptional repressors;Boldrin;Nucleic Acids Res,2010
4. Effects of nucleoid-associated proteins on bacterial chromosome structure and gene expression;Browning;Curr Opin Microbiol,2010
5. DNA topoisomerases: structure, function, and mechanism;Champoux;Annu Rev Biochem,2001
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