1. Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK
2. Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK
3. Barts Heart Centre, St Bartholomew’s Hospital, London EC1A 7BE, UK
4. College of Health and Life Sciences, Hamad Bin Khalifa University, Doha PO 34110, Qatar
5. NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK