The Role of Ertapenem for the Treatment of Complicated Intra-abdominal Infections With a Positive Culture for Enterococcus faecalis-Reference-Cited by-同舟云学术

The Role of Ertapenem for the Treatment of Complicated Intra-abdominal Infections With a Positive Culture for Enterococcus faecalis

Published:2018-12-15 Issue:1 Volume:6 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Fabre Valeria¹,Nemati Koorosh²,Avdic Edina³,Cosgrove Sara E¹,Amoah Joe²,Tamma Pranita D²

Affiliation:

1. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland

2. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland

3. Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland

Abstract

Abstract Controversy remains as to whether Enterococcus faecalis recovered from intra-abdominal infections (IAIs) requires targeted therapy. In a multicenter study comparing patients with IAIs from which E. faecalis was identified in intra-abdominal cultures, no difference in clinical outcomes was observed between patients receiving ertapenem vs those receiving piperacillin/tazobactam.

Funder

Investigator-Initiated Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/6/1/ofy339/33575959/ofy339.pdf

Reference10 articles.

1. Intra-abdominal infections: etiology, epidemiology, microbiological diagnosis and antibiotic resistance;Nicoletti;J Chemother,2009

2. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America;Solomkin;Surg Infect (Larchmt),2010

3. Ertapenem versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections: results of a double-blind, randomized comparative phase III trial;Solomkin;Ann Surg,2003