Time to rethink the law on part-human chimeras

Author:

Koplin Julian J12,Savulescu Julian123ORCID

Affiliation:

1. Biomedical Ethics Research Group, Murdoch Children's Research Institute, Parkville VIC 3052, Australia

2. Melbourne Law School, Carlton VIC 3053, Australia

3. Oxford Uehiro Centre for Practical Ethics, Oxford OX1 1PT, United Kingdom

Abstract

Abstract It may soon be possible to generate human tissues and organs inside of part-human chimeras via a technique known as interspecies blastocyst complementation. Using Australian legislation as a case study, we show why this technique of creating part-human chimeras falls within the gaps of existing legislation. We give an overview of the key ethical issues raised by part-human chimera research, and we describe how well these issues are met by a range of possible regulatory approaches. We ultimately argue that regulation of part-human chimera research should be (re)designed to balance two key aims: to facilitate ethical research involving part-human chimeras and to prevent unethical experimentation with chimeras that have an uncertain—and potentially substantial—degree of moral status.

Funder

Wellcome Trust

Victorian State Government

Publisher

Oxford University Press (OUP)

Subject

Law,Biochemistry, Genetics and Molecular Biology (miscellaneous),Medicine (miscellaneous)

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