Endogenously produced ganglioside GM3 endows etoposide and doxorubicin resistance by up-regulating Bcl-2 expression in 3LL Lewis lung carcinoma cells

Author:

Noguchi Mariko,Kabayama Kazuya,Uemura Satoshi,Kang Byoung-won,Saito Masaki,Igarashi Yasuyuki,Inokuchi Jin-ichi

Publisher

Oxford University Press (OUP)

Subject

Biochemistry

Reference35 articles.

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2. De Maria, R. , Lenti, L., Malisan, F., d’Agostino, F., Tomassini, B., Zeuner, A., Rippo, M.R., and Testi, R. (1997) Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis. Science, 277, 1652–1655.

3. Fridman, J.S. and Lowe, S.W. (2003) Control of apoptosis by p53. Oncogene, 22, 9030–9040.

4. Ha, K.T. , Lee, Y.C., and Kim, C.H. (2004) Overexpression of GD3 synthase induces apoptosis of vascular endothelial ECV304 cells through downregulation of Bcl-2. FEBS Lett., 568, 183–187.

5. Hakomori, S. (2002) Glycosylation defining cancer malignancy: new wine in an old bottle. Proc. Natl. Acad. Sci. U.S.A., 99, 10231–10233.

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