Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition

Author:

Costopoulos Charis1,Timmins Lucas H234,Huang Yuan56,Hung Olivia Y2,Molony David S3,Brown Adam J1,Davis Emily L3,Teng Zhongzhao67,Gillard Jonathan H6,Samady Habib23,Bennett Martin R1

Affiliation:

1. Division of Cardiovascular Medicine, University of Cambridge, Level 6, ACCI, Hills Road, Addenbrooke’s Hospital, Cambridge, UK

2. Division of Cardiology, Department of Medicine, Andreas Gruentzig Cardiovascular Center, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA, USA

3. Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA, USA

4. Department of Bioengineering, University of Utah, 50 S. Central Campus Drive, Salt Lake City, UT, USA

5. EPSRC Centre for Mathematical and Statistical Analysis of Multimodal Imaging, University of Cambridge, 20 Clarkson Road, Cambridge, UK

6. Department of Radiology, University of Cambridge, Hills Road, Addenbrooke's Hospital, Cambridge, UK

7. Department of Engineering, University of Cambridge, Hills Road, Addenbrooke's Hospital, Cambridge, UK

Funder

British Heart Foundation

Heart Research UK

MRC

NIHR

Cambridge Biomedical Research Centre

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

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