Cardiovascular prevention: sometimes dreams can come true

Author:

Ferrari Roberto1,Cimaglia Paolo1,Cantone Anna1,Serenelli Matteo1,Guardigli Gabriele1

Affiliation:

1. Cardiovascular Research Centre, Ferrara University , Via Aldo Moro 8, 44124 Ferrara , Italy

Abstract

Abstract Cardiovascular disease (CVD) is a chronic condition driven by the complex interaction of different risk factors including genetics, lifestyle, environment, etc. which, differently from other pathologies, can be prevented. Treatment of CVD has been inconceivably successful but now it seems that it has reached a plateau suggesting that prevention is the way forward. However, the COVID-19 pandemic has spotted all the limits of the actual health system regarding territorial and, particularly, of preventive medicine. To this end, recently, the SCORE2 risk prediction algorithms, a contemporary model to estimate 10 years risk of CVD in Europe and the new guidelines on prevention have been released. The present review article describes a dream: how prevention of CVD should be addressed in the future. New concepts and paradigms like early genetically personalized and imaging driven risk factors, cardiac risk cartography, measurements of the exposome, estimation of costs of a delayed outcome vs. healthy lifespan, are all addressed. We highlight the importance of technologies and the concept of being engaged in a ‘healthy’ and not just ‘sick’ system as it is today. The concept of ‘clearing house’ with a ‘care health team’ instead of a ‘heart team’ is described. Finally, we articulate the four points necessary for the dream to come true.

Funder

Fondazione Anna Maria Sechi per il Cuore

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine

Reference22 articles.

1. The new SCORE2 risk prediction algorithms and the growing challenge of risk factors not captured by traditional risk scores;Crea;Eur Heart J,2021

2. SCORE2 Risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe;SCORE2 Working Group and ESC Cardiovascular Risk Collaboration;Eur Heart J,2021

3. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: A report of the American college of cardiology/American heart association task force on clinical practice guidelines;Arnett;Circulation,2019

4. 2021 ESC guidelines on cardiovascular disease prevention in clinical practice;Visseren;Eur Heart J,2021

5. Association of genetic variants related to combined exposure to lower low-density lipoproteins and lower systolic blood pressure with lifetime risk of cardiovascular disease;Ference;JAMA,2019

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