Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

Author:

Ference Brian A.12,Bhatt Deepak L.3,Catapano Alberico L.4,Packard Chris J.5,Graham Ian6,Kaptoge Stephen2,Ference Thatcher B.1,Guo Qi12,Laufs Ulrich7,Ruff Christian T.8,Cupido Arjen19,Hovingh G. Kees9,Danesh John2,Holmes Michael V.10,Smith George Davey11,Ray Kausik K.12,Nicholls Stephen J.13,Sabatine Marc S.8

Affiliation:

1. Centre for Naturally Randomized Trials, University of Cambridge, Cambridge, United Kingdom

2. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

3. Brigham and Women’s Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts

4. Department of Pharmacological and Biomolecular Sciences, University of Milan, Multimedica IRCCS, Milano, Italy

5. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom

6. School of Medicine, Trinity College, Dublin, Ireland

7. Department of Cardiology, University of Leipzig, Leipzig, Germany

8. Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts

9. Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands

10. MRC Population Health Research Unit, Clinical Trial Service Unit, and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

11. MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom

12. School of Public Health, Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London, London, United Kingdom

13. Monash University, Melbourne, Australia

Publisher

American Medical Association (AMA)

Subject

General Medicine

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