SysMod: the ISCB community for data-driven computational modelling and multi-scale analysis of biological systems

Author:

Dräger Andreas1234,Helikar Tomáš5,Barberis Matteo678,Birtwistle Marc9,Calzone Laurence10,Chaouiya Claudine1112,Hasenauer Jan13,Karr Jonathan R14,Niarakis Anna1516,Rodríguez Martínez María17,Saez-Rodriguez Julio18,Thakar Juilee1920

Affiliation:

1. Computational Systems Biology of Infections and Antimicrobial-Resistant Pathogens, Institute for Bioinformatics and Medical Informatics (IBMI), University of Tübingen, 72076 Tübingen, Germany

2. Department of Computer Science, University of Tübingen, 72076 Tübingen, Germany

3. German Center for Infection Research (DZIF), Partner Site, Tübingen, Germany

4. Cluster of Excellence ‘Controlling Microbes to Fight Infections’, University of Tübingen, Tübingen, Germany

5. Department of Biochemistry, University of Nebraska, Lincoln, NE 68588-0664, USA

6. Systems Biology, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, Surrey, UK

7. Centre for Mathematical and Computational Biology, CMCB, University of Surrey, Guildford GU2 7XH, Surrey, UK

8. Synthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands

9. Department of Chemical and Biomolecular Engineering, Clemson University, Clemson, SC 29634, USA

10. Institut Curie, PSL Research University, Mines Paris Tech, Inserm, U900, F-75005 Paris, France

11. Aix-Marseille Université, CNRS, Centrale Marseille, I2M, Marseille 2780-156, France

12. Instituto Gulbenkian de Ciência, Oeiras 2780-156, Portugal

13. Interdisicplinary Research Unit Mathematics and Life Sciences, University of Bonn, Bonn 53115, Germany

14. Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA

15. GenHotel, University of Evry, University of Paris-Saclay, Genopole, Évry 91025, France

16. Lifeware Group, Inria Saclay-île de France, 91120 Palaiseau, France

17. IBM Research Europe, Zurich, CH–8803 Rüschlikon, Switzerland

18. Heidelberg University, Faculty of Medicine and Heidelberg University Hospital, Institute of Computational Biomedicine, 69120 Heidelberg, Germany

19. Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA

20. Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA

Abstract

Abstract Computational models of biological systems can exploit a broad range of rapidly developing approaches, including novel experimental approaches, bioinformatics data analysis, emerging modelling paradigms, data standards and algorithms. A discussion about the most recent advances among experts from various domains is crucial to foster data-driven computational modelling and its growing use in assessing and predicting the behaviour of biological systems. Intending to encourage the development of tools, approaches and predictive models, and to deepen our understanding of biological systems, the Community of Special Interest (COSI) was launched in Computational Modelling of Biological Systems (SysMod) in 2016. SysMod’s main activity is an annual meeting at the Intelligent Systems for Molecular Biology (ISMB) conference, which brings together computer scientists, biologists, mathematicians, engineers, computational and systems biologists. In the five years since its inception, SysMod has evolved into a dynamic and expanding community, as the increasing number of contributions and participants illustrate. SysMod maintains several online resources to facilitate interaction among the community members, including an online forum, a calendar of relevant meetings and a YouTube channel with talks and lectures of interest for the modelling community. For more than half a decade, the growing interest in computational systems modelling and multi-scale data integration has inspired and supported the SysMod community. Its members get progressively more involved and actively contribute to the annual COSI meeting and several related community workshops and meetings, focusing on specific topics, including particular techniques for computational modelling or standardisation efforts.

Funder

DFG

German Research Foundation

National Institutes of Health

NIH

Horizon 2020

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

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