popFBA: tackling intratumour heterogeneity with Flux Balance Analysis

Author:

Damiani Chiara12,Di Filippo Marzia13,Pescini Dario14,Maspero Davide3,Colombo Riccardo12,Mauri Giancarlo12

Affiliation:

1. SYSBIO Centre of Systems Biology, Milan, Italy

2. Department of Informatics, Systems and Communication, University Milano-Bicocca, Milan, Italy

3. Department of Biotechnology and Biosciences, University Milano-Bicocca, Milan, Italy

4. Department of Statistics and Quantitative Methods, University Milano-Bicocca, Milan, Italy

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference24 articles.

1. Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes;Bordel;PLoS Comput. Biol,2010

2. The causes and consequences of genetic heterogeneity in cancer evolution;Burrell;Nature,2013

3. Cancer cell metabolism: one hallmark, many faces;Cantor;Cancer Disc,2012

4. Computational strategies for a system-level understanding of metabolism;Cazzaniga;Metabolites,2014

5. An ensemble evolutionary constraint-based approach to understand the emergence of metabolic phenotypes;Damiani;Nat. Comput,2014

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