BTR: a bioinformatics tool recommendation system

Author:

Green Ryan1,Qu Xufeng2,Liu Jinze2,Yu Tingting3ORCID

Affiliation:

1. Department of Computer Science, University of Cincinnati , Cincinnati 45219, United States

2. Department of Biostatistics, Virginia Commonwealth University , Richmond 23284, United States

3. School of Computing, University of Connecticut , Storrs 06269, United States

Abstract

Abstract Motivation The rapid expansion of Bioinformatics research has led to a proliferation of computational tools for scientific analysis pipelines. However, constructing these pipelines is a demanding task, requiring extensive domain knowledge and careful consideration. As the Bioinformatics landscape evolves, researchers, both novice and expert, may feel overwhelmed in unfamiliar fields, potentially leading to the selection of unsuitable tools during workflow development. Results In this article, we introduce the Bioinformatics Tool Recommendation system (BTR), a deep learning model designed to recommend suitable tools for a given workflow-in-progress. BTR leverages recent advances in graph neural network technology, representing the workflow as a graph to capture essential context. Natural language processing techniques enhance tool recommendations by analyzing associated tool descriptions. Experiments demonstrate that BTR outperforms the existing Galaxy tool recommendation system, showcasing its potential to streamline scientific workflow construction. Availability and implementation The Python source code is available at https://github.com/ryangreenj/bioinformatics_tool_recommendation.

Funder

University of Cincinnati Startup Grant

Publisher

Oxford University Press (OUP)

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