GateFinder: projection-based gating strategy optimization for flow and mass cytometry

Author:

Aghaeepour Nima12,Simonds Erin F3,Knapp David J H F4,Bruggner Robert V1,Sachs Karen1,Culos Anthony2,Gherardini Pier Federico1,Samusik Nikolay1,Fragiadakis Gabriela K1,Bendall Sean C15,Gaudilliere Brice12,Angst Martin S2,Eaves Connie J4,Weiss William A3,Fantl Wendy J6,Nolan Garry P1

Affiliation:

1. Baxter Laboratory in Stem Cell Biology

2. Department of Anesthesiology, Stanford University, Stanford, CA, USA

3. Department of Neurology, University of California, San Francisco, CA, USA

4. Terry Fox Laboratory, British Columbia Cancer Research Center, Vancouver, BC, Canada

5. Department of Pathology

6. Department of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA

Funder

Ann Schreiber Mentored Investigator Award

Ovarian Cancer Research Fund

Canadian Institute of Health Research

CIHR

Postdoctoral Fellowship

International Society for Advancement of Cytometry Scholarship

Damon Runyon Cancer Research Foundation Postdoctoral Fellowship

March of Dimes Prematurity Research Center at Stanford University

Gates Foundations

Department of Anesthesiology, Perioperative and Pain Medicine

Stanford University

National Institute of Health

NIH

California Institute for Regenerative Medicine

European Commission

FDA

Entertainment Industry Foundation

Cure Starts Now Foundation

Terry Fox Foundation Program Project

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference7 articles.

1. A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes;Aghaeepour;Cytometry A,2016

2. Cell type discovery and representation in the era of high-content single cell phenotyping;Bakken;BMC Bioinformatics,2017

3. Immunologic and virologic events in early HIV infection predict subsequent rate of progression;Ganesan;J. Infect. Dis,2010

4. Single‐cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3‐ITD‐mutated AML stem/progenitor cells;Han;Cytometry A,2015

5. Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2;Inoue;Cancer Cell,2016

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