Single-synapse analyses of Alzheimer’s disease implicate pathologic tau, DJ1, CD47, and ApoE-Reference-Cited by-同舟云学术

Single-synapse analyses of Alzheimer’s disease implicate pathologic tau, DJ1, CD47, and ApoE

Published:2021-12-17 Issue:51 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Phongpreecha Thanaphong¹²³^ORCID,Gajera Chandresh R.¹^ORCID,Liu Candace C.¹^ORCID,Vijayaragavan Kausalia¹^ORCID,Chang Alan L.²³⁴^ORCID,Becker Martin²³⁴^ORCID,Fallahzadeh Ramin²³⁴^ORCID,Fernandez Rosemary¹^ORCID,Postupna Nadia⁵^ORCID,Sherfield Emily⁵,Tebaykin Dmitry¹^ORCID,Latimer Caitlin⁵^ORCID,Shively Carol A.⁶^ORCID,Register Thomas C.⁶^ORCID,Craft Suzanne⁷,Montine Kathleen S.¹,Fox Edward J.¹,Poston Kathleen L.⁸⁹^ORCID,Keene C. Dirk⁵^ORCID,Angelo Michael¹^ORCID,Bendall Sean C.¹^ORCID,Aghaeepour Nima²³⁴^ORCID,Montine Thomas J.¹^ORCID

Affiliation:

1. Department of Pathology, Stanford University, Stanford, CA, USA.

2. Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, USA.

3. Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.

4. Department of Pediatrics, Stanford University, Stanford, CA, USA.

5. Department of Pathology, University of Washington, Seattle, WA, USA.

6. Department of Pathology/Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.

7. Department of Internal Medicine–Geriatrics, Wake Forest School of Medicine, Winston-Salem, NC, USA.

8. Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.

9. Department of Neurosurgery, Stanford University, Stanford, CA, USA.

Abstract

Multiplex single-synapse events from multiple regions of Alzheimer’s disease brain revealed new alterations unique to humans.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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