Three-dimensional cardiovascular imaging-genetics: a mass univariate framework

Author:

Biffi Carlo12ORCID,de Marvao Antonio2,Attard Mark I2,Dawes Timothy J W23,Whiffin Nicola234,Bai Wenjia1,Shi Wenzhe1,Francis Catherine34,Meyer Hannah5,Buchan Rachel34,Cook Stuart A23467,Rueckert Daniel1,O’Regan Declan P2

Affiliation:

1. Department of Computing, Imperial College London, South Kensington Campus, London, UK

2. Cardiovascular Magnetic Resonance Imaging and Genetics, MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital Campus, London, UK

3. Quantitative Physiology and Genetics, National Heart and Lung Institute, Imperial College London, London, UK

4. NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK

5. European Molecular Biology Laboratory (EMBL), European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK

6. Department of Cardiology, National Heart Centre Singapore, Singapore

7. Programme in Cardiovascular and Metabolic Disorders, Duke National University Singapore, Singapore

Funder

British Heart Foundation

Academy of Medical Sciences

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference35 articles.

1. Genome-wide association study identifies single-nucleotide polymorphism in kcnb1 associated with left ventricular mass in humans: the hypergen study;Arnett;BMC Med. Genet,2009

2. A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion;Bai;Med. Image Anal,2015

3. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamin;J. R. Stat. Soc. Ser. B,1995

4. Adaptive linear step-up procedures that control the false discovery rate;Benjamini;Biometrika,2006

5. The control of the false discovery rate in multiple testing under dependency;Benjamini;Ann. Stat,2001

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