Mian: interactive web-based microbiome data table visualization and machine learning platform

Author:

Jin Boyang Tom1ORCID,Xu Feng2,Ng Raymond T3,Hogg James C2

Affiliation:

1. Department of Computer Science, Stanford University, Stanford, CA, USA 94305

2. Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada V6Z1Y6

3. Department of Computer Science, University of British Columbia, Vancouver, BC, Canada V6T1Z4

Abstract

Abstract Summary Mian is a web application to interactively visualize, run statistical tools and train machine learning models on operational taxonomic unit (OTU) or amplicon sequence variant (ASV) datasets to identify key taxonomic groups, diversity trends or taxonomic composition shifts in the context of provided categorical or numerical sample metadata. Tools, including Fisher’s exact test, Boruta feature selection, alpha and beta diversity, and random forest and deep neural network classifiers, facilitate open-ended data exploration and hypothesis generation on microbial datasets. Availability Mian is freely available at: miandata.org. Mian is an open-source platform licensed under the MIT license with source code available at github.com/tbj128/mian. Supplementary information Supplementary data are available at Bioinformatics online.

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

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